With Protection in place and regular Exfoliation opening clear channels, it’s time for the fun part: actives (we call them Additives). These molecules don’t just sit on top of the skin—they deliver precise biochemical instructions that nudge cells to make more collagen, dial down pigment, or rebuild the barrier. Below is a 2025 snapshot of the most evidence-backed, non-prescription anti-ageing ingredients you can safely discuss on an Australian public website.
L-ascorbic acid is both a co-factor for pro-collagen enzymes and a formidable free-radical quencher. A 2024 systematic review of 32 clinical studies ranked vitamin C alongside retinol as a Grade A cosmeceutical for visible anti-ageing, citing consistent gains in dermal density and brightness after 8-12 weeks SpringerLink. Stabilised derivatives such as 3-O-ethyl ascorbic acid and tetra-isopalmitoyl ascorbic acid extend shelf-life while delivering similar collagen perks.
Topical exosomes derived from fibroblasts carry micro-RNAs that stimulate collagen and quell UV inflammation; a 2024 literature review summarised early trials showing pore refinement and tone evening within four weeks Wiley Online Library.
Liposomal photolyase—a light-activated DNA-repair enzyme—snips UV-induced cyclobutane dimers; small case series note smoother texture and less actinic erythema after three months of nightly use jidonline.org.
While still niche, these actives hint at the next frontier where skincare meets regenerative medicine.
Additives are the construction crew—they lay new bricks and reinforce old beams. But they can only do their best work if:
For other concerns—acne, rosacea, precancerous lesions—bespoke actives and often prescription-only agents exist; our clinicians can advise privately. On the public stage, these non-prescription stars give everyone a legal, accessible way to age on their own terms.
Blend these thoughtfully, respect your skin’s pace, and watch the biology of ageing slow to a graceful stroll.
Peach Cosmetic Medicine